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Neisseria gonorrhoeae triggers the PGE2/IL-23 pathway and promotes IL-17 production by human memory T cells

✍ Scribed by Stefanelli, Paola; Teloni, Raffaela; Carannante, Anna; Mariotti, Sabrina; Nisini, Roberto; Gagliardi, Maria Cristina


Book ID
123043162
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
337 KB
Volume
99
Category
Article
ISSN
0090-6980

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## Abstract Ligands of the aryl hydrocarbon receptor (AHR), a transcription factor mediating the effects of dioxin, favor Th17 differentiation and exacerbate autoimmunity in mice. We investigated how AHR ligands affected human T‐cell polarization. We found that the high affinity and stable AHR‐liga