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Prostaglandin E2 and IL-23 plus IL-1β Differentially Regulate the Th1/Th17 Immune Response of Human CD161+CD4+ Memory T Cells

✍ Scribed by Arthur Barrie; Anupriya Khare; Matthew Henkel; Yingze Zhang; M. Michael Barmada; Richard Duerr; Anuradha Ray


Book ID
114902126
Publisher
Wiley (Blackwell Publishing)
Year
2011
Tongue
English
Weight
878 KB
Volume
4
Category
Article
ISSN
1752-8054

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The role of TGF-g 1 in the regulation of T cell responses has been perplexing, possibly because it is dependent on the type of T cell being regulated and its cytokine microenvironment. In the present study, we demonstrate that TGF-g 1 has a profound inhibitory effect on naive CD4 + T cell undergoing