Negative Regulation of Human Astrocytes by Interferon (IFN) α in Relation to Growth Inhibition and Impaired Glucose Utilization

Biological effects of γ-interferon on hu

Biological effects of γ-interferon on human tumor cells: Quantity and affinity of cell membrane receptors for γ-IFN in relation to growth inhibition and induction of HLA-DR expression

✍ Ugur Ücer; Helge Bartsch; Peter Scheurich; Klaus Pfizenmaier 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 521 KB

## Abstract A large difference in the number of γ‐IFN receptors was found on a variety of human tumor cell lines with a range of 0.4 to 15 × 10^3^ binding sites/cell. The receptor number did not correlate with the potential responsiveness of the cells to γ‐IFN, in regard to either growth inhibition