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Negative regulation of FcεRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b

✍ Scribed by Qu, Xiujuan (author);Sada, Kiyonao (author);Kyo, Shinkou (author);Maeno, Koichiro (author);Miah, S. M.Shahjahan (author);Yamamura, Hirohei (author)

Book ID
121658041
Publisher
American Society of Hematology
Year
2004
Tongue
English
Weight
354 KB
Volume
103
Category
Article
ISSN
0006-4971

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## Abstract **Background:** Recent studies have demonstrated that c‐Cbl functions as a ubiquitin‐protein ligase toward immune receptors and non‐receptor protein‐tyrosine kinase Syk by facilitating their ubiquitination and subsequent targeting to proteasomes. However, it was not clear whether Src fa