Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA
โ Scribed by Rossi, John J; Unwalla, Hoshang J; Li, Ming-Jie; Kim, James D; Li, Hai Tang; Ehsani, Ali; Alluin, Jessica
- Book ID
- 109908322
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 382 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1087-0156
- DOI
- 10.1038/nbt1040
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract MicroRNAs (miRs) are short endogenous RNAs that regulate gene expression by incomplete pairing with messenger RNAs. An increasing number of studies show that mammalian microRNAs play fundamental roles in various aspects of cellular function including differentiation, proliferation, and
HIV-1 and HIV-2 are co-endemic in certain geographic areas. HIV-2 is more weakly pathogenic than HIV-1, and progression to AIDS occurs less frequently and over a longer period of time. Recent epidemiologic studies suggest that individuals infected with HIV-2 have a lower risk of HIV-1 infection. Bot