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Expression of interfering RNAs from an HIV-1 Tat-inducible chimeric promoter

✍ Scribed by Viraj R. Sanghvi; Laura F. Steel


Book ID
116968491
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
808 KB
Volume
155
Category
Article
ISSN
0168-1702

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## Abstract Opiates exacerbate human immunodeficiency virus type 1 (HIV‐1) Tat~1‐72~‐induced release of key proinflammatory cytokines by astrocytes, which may accelerate HIV neuropathogenesis in opiate abusers. The release of monocyte chemoattractant protein‐1 (MCP‐1, also known as CCL2), in partic