𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Nefazodone in vitro: Metabolic conversions, and inhibition of P450-3A isoforms.

✍ Scribed by Von Moltke, L.L.; Greenblatt, D.J.; Schmider, J.; Harmatz, J.S; Shader, R.I.

Book ID
110019627
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
148 KB
Volume
59
Category
Article
ISSN
0009-9236

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Inhibition of human cytochrome P450 isof
Inhibition of human cytochrome P450 isoforms in vitro by zafirlukast
✍ Richard I. Shader; Brian W. Granda; Lisa L. von Moltke; Gina M. Giancarlo; David πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 135 KB πŸ‘ 1 views

Zafirlukast is a cysteinyl leukotriene antagonist used to treat allergic and exercise-induced asthma. This in vitro study used human liver microsomes to evaluate the inhibitory activity of zafirlukast versus six human cytochrome P450 (CYP) isoforms. Zafirlukast (0 -250 mM) was co-incubated with fixe

The role of different cytochrome P450 is
The role of different cytochrome P450 isoforms in in vitro chloroform metabolism
✍ Testai, Emanuela ;De Curtis, Valentina ;Gemma, Simonetta ;Fabrizi, Laura ;Gervas πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 111 KB πŸ‘ 2 views

The two CHCl3 activation pathways have been studied in incubations at different oxygenation conditions with hepatic microsomes from control Sprague Dawley (SD) rats or SD rats treated with different cytochrome P450 inducers (acetone, phenobarbital, pyrazole, dexamethasone, and beta-naphthoflavone).