Estimation of the effective amount enter
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Y. Plusquellec; G. Houin
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Article
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1995
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Elsevier Science
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English
โ 475 KB
A pharmacokinetic model is used to take into account multiple recirculations of drug occurring at various times after gall bladder emptying. If a dose D is initially administered, due to recirculation, an effective amount A\* reaches the body. This value A\* is expressed as a function of D and the m