𝔖 Bobbio Scriptorium
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Estimation of area under the curve for drugs subject to enterohepatic cycling

✍ Scribed by Theresa A. Shepard; Richard H. Reuning; Leon J. Aarons


Book ID
112472198
Publisher
Springer
Year
1985
Tongue
English
Weight
1005 KB
Volume
13
Category
Article
ISSN
1573-8744

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Estimation of the effective amount enter
✍ Y. Plusquellec; G. Houin πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 475 KB

A pharmacokinetic model is used to take into account multiple recirculations of drug occurring at various times after gall bladder emptying. If a dose D is initially administered, due to recirculation, an effective amount A\* reaches the body. This value A\* is expressed as a function of D and the m