Detection of Hydroxyl Radicals by d-Phen
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Roberto Biondi; Yong Xia; Ruggero Rossi; Nazareno Paolocci; Giuseppe Ambrosio; J
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Article
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2001
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Elsevier Science
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English
β 177 KB
Hydroxylation of l-phenylalanine (Phe) by hydroxyl radical (\*OH) yields 4-, 3-, and 2-hydroxyl-Phe (para-, meta-, and ortho-tyrosine, respectively). Phe derivative measurements have been employed to detect \*OH formation in cells and tissues, however, the specificity of this assay is limited since