The effects of chronic morphine treatmen
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Daniel Luttinger; Susan K. Burgess; Charles B. Nemeroff; Arthur J. Prange
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Article
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1983
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Springer
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English
โ 411 KB
Previous studies have shown that the opioid antagonist naloxone does not alter neurotensin (NT)-induced antinociception. In the present studies, tolerance to morphine in mice significantly attenuated NT-induced antinociception, but not NT-induced hypothermia. In addition, centrally administered NT i