Naturally occurring testis-specific histone H3 antisense transcripts in Drosophila
β Scribed by Anna Akhmanova; Hannie Kremer; Koos Miedema; Wolfgang Hennig
- Book ID
- 111659053
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 356 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1040-452X
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The testis-specific histone H1t is synthesized during spermatogenesis exclusively in late pachytene primary spermatocytes. Transcription of the H1t gene is repressed in every tissue except testis. Within the testis, transcription is repressed during development before the spermatocyte stage and in l
## Abstract The Xβbox binding protein RFX4 is highly expressed in testis in contrast with other tissues, but its function there is unknown. Another family member abundant in testis, RFX2, has been shown to bind to the XβBox elements in the promoter of the testis specific histone H1t, which is expre
## Abstract Previous work in our laboratory revealed upregulated transcription of the testisβspecific linker histone __H1t__ gene in pachytene primary spermatocytes during spermatogenesis. Using the H1t Xβbox as an affinity chromatography probe, we identified Regulatory Factor X2 (RFX2), a member o
## Abstract The testisβspecific linker histone H1t is transcribed exclusively in pachytene spermatocytes during spermatogenesis. The H1t promoter contains two imperfect inverted repeats which together comprise the Xβbox motif that is known to bind the transcription factor regulatory factor X (RFX).