Resistance mutations to hepatitis C virus (HCV) nonstructural protein 3 (NS3) protease inhibitors in <1% of the viral quasispecies may still allow >1000-fold viral load reductions upon treatment, consistent with their reported reduced replicative fitness in vitro. Recently, however, an R155K proteas
✦ LIBER ✦
Naturally-occurring hepatitis C virus protease variants: implications for resistance to new antivirals
✍ Scribed by F.X. López-Labrador; A. Moya; F. González-Candelas
- Book ID
- 117770865
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 145 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1386-6532
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