✦ LIBER ✦

Characterization of naturally occurring protease inhibitor-resistance mutations in genotype 1b hepatitis C virus patients

✍ Scribed by Hiroko Shindo; Shinya Maekawa; Kazuki Komase; Ryota Sueki; Mika Miura; Makoto Kadokura; Kuniaki Shindo; Fumitake Amemiya; Takatoshi Kitamura; Yasuhiro Nakayama; Taisuke Inoue; Minoru Sakamoto; Shun-ichi Okada; Yasuhiro Asahina; Namiki Izumi; Masao Honda; Shuichi Kaneko; Nobuyuki Enomoto

Book ID: 113094656
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 314 KB
Volume: 6
Category: Article
ISSN: 1936-0533
DOI: 10.1007/s12072-011-9306-7

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

669 CHARACTERIZATION OF PROTEASE INHIBIT

669 CHARACTERIZATION OF PROTEASE INHIBITOR RESISTANCE MUTATIONS IN UNTREATED PATIENTS INFECTED WITH GENOTYPE 1B HEPATITIS C VIRUS

✍ H. Shindo; S. Maekawa; M. Miura; K. Komase; M. Kadokura; R. Sueki; F. Amemiya; T 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 47 KB

Naturally occurring hepatitis C virus (H

Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy

✍ Vicenti, I.; Rosi, A.; Saladini, F.; Meini, G.; Pippi, F.; Rossetti, B.; Sidella 📂 Article 📅 2012 🏛 Oxford University Press 🌐 English ⚖ 171 KB

Naturally occurring dominant resistance

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients

✍ Thomas Kuntzen; Joerg Timm; Andrew Berical; Niall Lennon; Aaron M. Berlin; Sarah 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 263 KB

Resistance mutations to hepatitis C virus (HCV) nonstructural protein 3 (NS3) protease inhibitors in <1% of the viral quasispecies may still allow >1000-fold viral load reductions upon treatment, consistent with their reported reduced replicative fitness in vitro. Recently, however, an R155K proteas

Naturally occurring genotype 2b/1a hepat

Naturally occurring genotype 2b/1a hepatitis C virus in the United States

✍ Dipankar Bhattacharya; Molly A Accola; Israr H Ansari; Rob Striker; William M Re 📂 Article 📅 2011 🏛 BioMed Central 🌐 English ⚖ 494 KB

743 NATURALLY OCCURRING DRUG RESISTANCE

743 NATURALLY OCCURRING DRUG RESISTANCE MUTATIONS IN THE HEPATITIS C VIRUS NS3 PROTEASE IN HIV/HCV COINFECTED PATIENTS TREATED WITH HIV PROTEASE INHIBITORS

✍ M. Bottecchia; A. Madejón; M. Sánchez-Carillo; P. Labarga; J. García-Samaniego; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 48 KB

Characterization of resistance to the pr

Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus–infected patients

✍ Simone Susser; Christoph Welsch; Yalan Wang; Markus Zettler; Francisco S. Doming 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 543 KB

Boceprevir is a hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor that is currently being evaluated in combination with peginterferon alfa-2b and ribavirin in phase 3 studies. The clinical resistance profile of boceprevir is not characterized in detail so far. The NS3 protea