Naturally occurring hepatitis B virus mutants with deletions in the core promoter region
โ Scribed by Tomasz Laskus; Jorge Rakela; Myron J. Tong; Marek J. Nowicki; James W. Mosley; David H. Persing
- Book ID
- 118566154
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 439 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0168-8278
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๐ SIMILAR VOLUMES
The core promoter region of hepatitis B virus genomes regulates transcription of the precore and pregenomic mRNAs encoding hepatitis B e antigen (HBeAg) and core antigen that contain target epitopes for cytotoxic T lymphocytes. The prevalence and clinical significance of mutations in this region wer
## Abstract Although Korea is one of the endemic areas for hepatitis B virus infection (HBV), the prevalence of deletions in HBV preS region occurring naturally have not been determined. In the present study, the prevalence of preS deletions was determined in terms of clinical state and HBeAg seros