Natural variation in replicative and chronological life spans of Saccharomyces cerevisiae
β Scribed by Hong Qin; Meng Lu
- Book ID
- 113614753
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 226 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0531-5565
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Chronological lifespan may be defined as the result of accumulation of irreversible damage to intracellular components during extended stationary phase, compromising cellular integrity and leading to death and autolysis. In contrast, replicative lifespan relates to the number of divisions an individ
From a UV-irradiated sample of diploid cells several clones were isolated, which produced cells with a shortened life span. A closer examination of three of these clones showed among other deviations from the wild type a higher sensitivity to UV-irradiation. Three other clones, which were selected f