Pyrrolizidine alkaloid (PA)-containing plants are widely distributed in the world. PAs are hepatotoxic, affecting livestock and humans. PA N-oxides are often present together with PAs in plants and also exhibit hepatotoxicity but with less potency. HPLC-MS is generally used to analyze PA-containing
✦ LIBER ✦
Natural Products || Pyrrolizidine Alkaloid-Induced Toxicity to the Liver
✍ Scribed by Ramawat, Kishan Gopal; Mérillon, Jean-Michel
- Book ID
- 120503515
- Publisher
- Springer Berlin Heidelberg
- Year
- 2013
- Weight
- 131 KB
- Category
- Article
- ISBN
- 3642221440
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Characteristic ion clusters as determina
✍
Jianqing Ruan; Na Li; Qingsu Xia; Peter P. Fu; Shuying Peng; Yang Ye; Ge Lin
📂
Article
📅
2012
🏛
John Wiley and Sons
🌐
English
⚖ 507 KB
Human liver microsomal reduction of pyrr
✍
Yu-Ping Wang; Jian Yan; Peter P. Fu; Ming W. Chou
📂
Article
📅
2005
🏛
Elsevier Science
🌐
English
⚖ 292 KB
Toxic effects and pyrrolic metabolites i
✍
A.R. Mattocks; I.N.H. White
📂
Article
📅
1973
🏛
Elsevier Science
🌐
English
⚖ 495 KB
Role of the Acid Moieties in the Toxic A
✍
MATTOCKS, A. R.
📂
Article
📅
1970
🏛
Nature Publishing Group
🌐
English
⚖ 254 KB
Role of cellular calcium homeostasis in
✍
Griffin, Donna S. ;Segall, H. J.
📂
Article
📅
1987
🏛
John Wiley and Sons
🌐
English
⚖ 699 KB
The pyrrolizidine alkaloid senecionine has been shown to be hepatotoxic, genotoxic, and cytotoxic. However, the biochemical mechanism by which senecionine produces hepatocellular toxicity remains to be elucidated. The role of calcium homeostasis in toxic liver injury was examined in isolated rat hep
Gene expression changes induced by the t
✍
Nan Mei; Lei Guo; Ruqing Liu; James C Fuscoe; Tao Chen
📂
Article
📅
2007
🏛
BioMed Central
🌐
English
⚖ 448 KB