## Abstract Methyl 6‐amino‐2,3‐dimethoxybenzoate (6) which was obtained from 6‐formyl‐2,3‐dimethoxybenzoic acid (1), was treated with phloroglucinol to give two new acridone alkaloids, 1,3,8‐trihydroxy‐7‐methoxy‐9‐acridone (7) and 1,3‐dihydroxy‐7,8‐dimethoxy‐9‐acridone (8). Methylation of 7 and 8 g
Natural product chemistry, 142. Synthesis of gravacridonol
✍ Scribed by Reisch, Johannes ;Voerste, A.
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 101 KB
- Volume
- 1991
- Category
- Article
- ISSN
- 0947-3440
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✦ Synopsis
Abstract
Gravacridonol (2), naturally occurring in the roots of Ruta graveolens, has been synthesized in one step from rutacridone (1) in a yield of 23%.
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## Abstract Two naturally occurring coumarins, dihydrosuberenol (5) and (__E__)‐__O__‐ethylsuberenol (6), and another possible natural product (__E__)‐__O__‐methylsuberenol (7), were synthesized from (__E__)‐suberenol (1). The treatment of 1 with HBr gave the new menthadienediylbis(coumarin) 8.
## Abstract Three new __rac__‐acridone‐coumarin dimers (acrimarins) 5, 6 and 7 have been obtained by condensation of (__E__)‐suberenol (1) with the corresponding acridones 2, 3 and 4.