๐”– Bobbio Scriptorium
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Natural peptide analgesics: the role of solution conformation

โœ Scribed by R. Spadaccini; P.A. Temussi

Book ID
105740560
Publisher
Springer
Year
2001
Tongue
English
Weight
557 KB
Volume
58
Category
Article
ISSN
1420-682X

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๐Ÿ“œ SIMILAR VOLUMES

Solution conformational preferences of a
Solution conformational preferences of a peptidic analogue of a natural macrolide
โœ Luca D. D'Andrea; Marco Mazzeo; Carla Isernia; Filomena Rossi; Michele Saviano; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 158 KB ๐Ÿ‘ 1 views

The conformational behavior in solution of a cyclic peptide with sequence cyclo-(Pro 1 -Pro 2 -Dab 3 (cHexA)c[N g HCO]-Leu 4 c[NHCO]-Suc 5 -Gly 6 -) has been throughly investigated with the combined use of nmr and molecular dynamic techniques. The compound, which has been modeled to mimic the FK506

Solution structure of nocistatin, a new
Solution structure of nocistatin, a new peptide analgesic
โœ Orlando Crescenzi; Remo Guerrini; Delia Picone; Severo Salvadori; Teodorico Tanc ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 139 KB

Nocistatin, a new heptadecapeptide encoded in the bPNP-3 gene, has a powerful biological activity connected with the mechanisms of pain transmission. It does not bind to the opioid receptors but to another brain receptor with high affinity. In order to substantiate these novel biological data with a

Conformational analysis of cyclic peptid
Conformational analysis of cyclic peptides in solution
โœ Horst Kessler; Jan-Willem Bats; Klaus Wagner; Martin Will ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 640 KB

## Synopsis The strategy and tactics of conformational analysis of cyclic peptides in solution is demonstrated by the example of cyclo(-D-Pro-Phe-TPhe-TYp-Phe-). Spin-locked experiments like rotating frame nuclear Overhauser enhancement spectroscopy (ROESY), ROTO, and TOCSY are successfully applie