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Natural IgM and IgG Antibodies to Thomsen-Friedenreich (T) Antigen in Serum of Patients with Gastric Cancer and Blood Donors: Relation to Lewis (a,b) Histo-blood Group Phenotype

✍ Scribed by Kurtenkov, Oleg

Book ID: 120350650
Publisher: Informa plc
Year: 1999
Tongue: English
Weight: 158 KB
Volume: 38
Category: Article
ISSN: 0284-186X
DOI: 10.1080/028418699432626

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## Abstract The TFA is a tumorassociated, bloodgrouprelated glycosidic precursor structure [Gal(β^1‐3^)GalNAc]. Its expression in carcinomas is accompanied by a decrease of natural TFA antibodies in serum. The relationship between the ABO(H)‐bloodgroup phenotype and natural anti‐TFA immune response