## Abstract In natural‐abundance ^13^C NMR spectrum of excised rat brain 55 resonances were resolved. The chemical shifts of most of the resonances were well correlated with those of pure brain metabolites, determined under identical experimental conditions. These resonances were also found in the
Natural abundance 13C NMR spectrum of glycogen in humans
✍ Scribed by T. Jue; J. A. B. Lohman; R. J. Ordidge; R. G. Shulman
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 193 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
In vivo NMR has focused on using "P and 'H to study metabolism in humans. Comparable "C NMR studies have not been undertaken, presumably, because of its insensitivity.
We report herein that the natural abundance I3C signal from CI glycogen is observable. The ability to observe the signal opens new opportunities to noninvasively study glycogen metabolism in man.
📜 SIMILAR VOLUMES
## Abstract When an isoalloxazine derivative (**1**) was reduced (**2**) its ^13^C‐NMR. resonances were all shifted upfield and the largest shifts were observed for C (4a), C(6) and C(8) but downfield shifts for C(2), C(4) and C(10a). The results and their biochemical implications are shortly discu
## Abstract Chemical shifts of ^13^C‐ and ^1^H‐NMR. spectra of vitamin D~3~ metabolites (**2–7**) are assigned. Substituent effect parameters due to hydroxyl groups are deduced by comparison with vitamin D~3~.
## Abstract Assignment of all ^13^C chemical shifts of perezone (1) and some derivatives was possible using time averaged 25·15 MHz spectra with the aid of proton noise modulated and CW decoupling. Rapid interconversion of tautomeric forms of 2,5‐dihydroxy‐1,4‐benzoquinones is deduced from the ^13^
## Abstract The transverse dephasing optimized (TDOP) approach can be used to obtain heteronuclear decoupling sequences that increase significantly coherence lifetimes in solid‐state NMR spectroscopy, leading to a dramatic improvement in the sensitivity of correlation experiments. Herein we demonst
## Abstract The integrated ^13^C NMR intensity of the glycogen Cl resonance was measured in skeletal muscle (biceps femoris region) of nine rabbits under __in vivo__ conditions. Concurrent chemical determinations of glycogen content showed that the __in vivo__ signal was 1.02 ± 0.06 the intensity o