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Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain

✍ Scribed by Birgitte Rahbek Kornum; Juliette Faraco; Emmanuel Mignot

Book ID
113553171
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
501 KB
Volume
21
Category
Article
ISSN
0959-4388

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## Abstract Chronic, daytime sleepiness is a major, disabling symptom for many patients with traumatic brain injury (TBI), but thus far, its etiology is not well understood. Extensive loss of the hypothalamic neurons that produce the wake‐promoting neuropeptide hypocretin (orexin) causes the severe