Nanotechnology Applications for Tissue Engineering

✍ Scribed by Sabu Thomas, Yves Grohens, Neethu Ninan

• Publisher: William Andrew
• Year: 2015
• Tongue: English
• Leaves: 312
• Series: Micro and Nano Technologies
• Edition: 1
• Category: Library

✦ Synopsis

Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. Researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. It provides substrates for cell adhesion and proliferation and agents for cell growth and can be used to create nanostructures and nanoparticles to aid the engineering of different types of tissue. Written by renowned scientists from academia and industry, this book covers the recent developments, trends and innovations in the application of nanotechnologies in tissue engineering and regenerative medicine. It provides information on methodologies for designing and using biomaterials to regenerate tissue, on novel nano-textured surface features of materials (nano-structured polymers and metals e.g.) as well as on theranostics, immunology and nano-toxicology aspects. In the book also explained are fabrication techniques for production of scaffolds to a series of tissue-specific applications of scaffolds in tissue engineering for specific biomaterials and several types of tissue (such as skin bone, cartilage, vascular, cardiac, bladder and brain tissue). Furthermore, developments in nano drug delivery, gene therapy and cancer nanotechonology are described. The book helps readers to gain a working knowledge about the nanotechnology aspects of tissue engineering and will be of great use to those involved in building specific tissue substitutes in reaching their objective in a more efficient way. It is aimed for R&D and academic scientists, lab engineers, lecturers and PhD students engaged in the fields of tissue engineering or more generally regenerative medicine, nanomedicine, medical devices, nanofabrication, biofabrication, nano- and biomaterials and biomedical engineering.

• Provides state-of-the-art knowledge on how nanotechnology can help tackling known problems in tissue engineering
• Covers materials design, fabrication techniques for tissue-specific applications as well as immunology and toxicology aspects
• Helps scientists and lab engineers building tissue substitutes in a more efficient way

✦ Table of Contents

Content:
Front-matter, Pages i,iii
Copyright, Page iv
List of Contributors, Pages xiii-xvi, António J. Almeida, R.S. Arathyram, Renu Geetha Bai, Ana Bettencourt, Anirbandeep Bose, Parvathy R. Chandran, R. Narayana Charyulu, Michael S. Detamore, Lídia M. Gonçalves, Yves Grohens, Prem N. Gupta, Ankush Jain, Sanjay Jain, Tippabattini Jayaramudu, Vaibhav Khare, Cheol Sang Kim, Se-Kwon Kim, Henriqueta Louro, Sivakumar Manickam, Neethu Mohan, Kasturi Muthoosamy, et al.
About the Editors, Page xvii
Preface, Page xix
Chapter 1 - Nanomedicine and Tissue Engineering, Pages 1-19, C.K. Sudhakar, Nitish Upadhyay, Arpit Verma, Ankush Jain, R. Narayana Charyulu, Sanjay Jain
Chapter 2 - Biomaterials: Design, Development and Biomedical Applications, Pages 21-44, Gownolla Malegowd Raghavendra, Kokkarachedu Varaprasad, Tippabattini Jayaramudu
Chapter 3 - Electrospinning of Polymers for Tissue Engineering, Pages 45-55, Afeesh Rajan Unnithan, R.S. Arathyram, Cheol Sang Kim
Chapter 4 - Biomimetic Nanofibers for Musculoskeletal Tissue Engineering, Pages 57-75, Neethu Mohan, Michael S. Detamore
Chapter 5 - Hydrogels—Promising Candidates for Tissue Engineering, Pages 77-94, C.K. Sudhakar, Nitish Upadhyay, Ankush Jain, Arpit Verma, R. Narayana Charyulu, Sanjay Jain
Chapter 6 - 3D Scaffolding for Pancreatic Islet Replacement, Pages 95-102, Neethu Ninan, Pradeep Manaloor Simonkutty, Sabu Thomas, Yves Grohens
Chapter 7 - Scaffolds with Antibacterial Properties, Pages 103-123, Afeesh Rajan Unnithan, R.S. Arathyram, Cheol Sang Kim
Chapter 8 - Dermal Tissue Engineering: Current Trends, Pages 125-131, Neethu Ninan, Pradeep Manaloor Simonkutty, Sabu Thomas, Yves Grohens
Chapter 9 - Chitosan and Its Application as Tissue Engineering Scaffolds, Pages 133-147, Jayachandran Venkatesan, Se-Kwon Kim, Tin Wui Wong
Chapter 10 - Cell Encapsulation in Polymeric Self-Assembled Hydrogels, Pages 149-171, Kokkarachedu Varaprasad, K. Vimala, Gownolla Malegowd Raghavendra, Tippabattini Jayaramudu, E.R. Sadiku, K. Ramam
Chapter 11 - Nanotechnology-Enabled Drug Delivery for Cancer Therapy, Pages 173-193, Anirbandeep Bose, Tin Wui Wong
Chapter 12 - Nanomedicine in Theranostics, Pages 195-213, Renu Geetha Bai, Kasturi Muthoosamy, Sivakumar Manickam
Chapter 13 - Upconversion Nanoparticles, Pages 215-220, Neethu Ninan, Pradeep Manaloor Simonkutty, Sabu Thomas, Yves Grohens
Chapter 14 - Gold Nanoparticles in Cancer Drug Delivery, Pages 221-237, Parvathy R. Chandran, Reny Thankam Thomas
Chapter 15 - Toxicology Considerations in Nanomedicine, Pages 239-261, Vaibhav Khare, Ajit K. Saxena, Prem N. Gupta
Chapter 16 - Role of Nanogenotoxicology Studies in Safety Evaluation of Nanomaterials, Pages 263-287, Henriqueta Louro, Ana Bettencourt, Lídia M. Gonçalves, António J. Almeida, Maria João Silva
Chapter 17 - Future of Nanotechnology in Tissue Engineering, Pages 289-306, Aruni Shajkumar
Index, Pages 307-315