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Nanoencapsulation of Stem Cells within Polyelectrolyte Multilayer Shells

✍ Scribed by Nalinkanth G. Veerabadran; Poorna L. Goli; Skylar S. Stewart-Clark; Yuri M. Lvov; David K. Mills

Book ID
102471933
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
206 KB
Volume
7
Category
Article
ISSN
1616-5187

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✦ Synopsis

Abstract

Mouse mesenchymal stem cells have been individually encased by polyelectrolyte layers of poly (L‐lysine) and hyaluronic acid using the electrostatic layer‐by‐layer assembly technique, resulting in a shell consisting of nanolayers of thickness around 6–9 nm. Maintenance of cell morphology and viability were demonstrated for up to one week. Further adjustments to shell permeability and flexibility will facilitate the use of these encapsulated cells in tissue engineering and targeted‐delivery applications.

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