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Name Reactions || Nenitzescu indole synthesis

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Book ID
118031438
Publisher
Springer Berlin Heidelberg
Year
2006
Weight
92 KB
Category
Article
ISBN
3540300309

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The solid-phase version of the Nenitzescu indole synthesis of 5-hydroxyindole-3-carboxamides is reported. This process involves initial acetoacetylation of ArgoPore 1 -Rink-NH 2 resin with diketene to aord a polymer-bound acetoacetamide. Formation of the corresponding enaminones via condensation wit

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Lewis acid catalyzed nenitzescu indole s
✍ Valeriya S. Velezheva; Albert G. Kornienko; Sergey V. Topilin; Ascar D. Turashev 📂 Article 📅 2006 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 131 KB

## Abstract magnified image A novel method for Lewis acid catalyzed Nenitzescu indole syntheses of 5‐hydroxyindoles bearing different substituents in positions 1 )Alk, Bn, Ar), 2 )Me, Et, Ph), and 3 )COOEt, COMe, CONHPh) as well as tricyclic derivatives are reported. The method is simple, rapid, e