Negative naloxone effects in schizophren
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David S. Janowsky; David S. Segal; Alan Abrams; Floyd Bloom; Roger Guillemin
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Article
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1977
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Springer
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English
โ 202 KB
On the basis of the hypothesis that the opiate-like neuropeptides, such as beta-endorphin, may be involved in the etiology of schizophrenic symptoms, naloxone 1,2 mg and placebo were administered intravenously to 8 schizophrenic patients, using a double-blind, crossover design. Naloxone was not foun