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Na/H exchange-dependent cell volume and pH regulation and disturbances

✍ Scribed by Cala, Peter M; Anderson, Steven E; Cragoe, Edward J

Book ID
122606604
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
670 KB
Volume
90
Category
Article
ISSN
0300-9629

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We investigated intracellular pH (pHi) regulation in cultured human ciliary muscle cells by means of the pH-sensitive absorbance of 5(and 6)-carboxy-4',5'-dimethylfluorescein (CDMF). The steady-state pHi was 7.09 +/- 0.04 (n = 12) in CO2/HCO3(-)-buffered and 6.86 +/- 0.03 (n = 12) in HEPES-buffered