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Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange

✍ Scribed by Christian Stock; Birgit Gassner; Christof R. Hauck; Hannelore Arnold; Sabine Mally; Johannes A. Eble; Peter Dieterich; Albrecht Schwab

Book ID
110113430
Publisher
Cambridge University Press
Year
2005
Tongue
English
Weight
378 KB
Volume
567
Category
Article
ISSN
0022-3751

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✍ Frank Stahl; Albrecht Lepple-Wienhues; Marianne Koch; Michael Wiederholt πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 887 KB

We investigated intracellular pH (pHi) regulation in cultured human ciliary muscle cells by means of the pH-sensitive absorbance of 5(and 6)-carboxy-4',5'-dimethylfluorescein (CDMF). The steady-state pHi was 7.09 +/- 0.04 (n = 12) in CO2/HCO3(-)-buffered and 6.86 +/- 0.03 (n = 12) in HEPES-buffered