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Nadph cytochrome P-450 reductase in rat, mouse and human brain

✍ Scribed by Vijayalakshmi Ravindranath; Hindupur K. Anandatheerthavarada; Susarla K. Shankar


Book ID
115781553
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
668 KB
Volume
39
Category
Article
ISSN
0006-2952

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## Abstract Summary: NADPH‐cytochrome P450 reductase (CPR or POR) is the obligatory electron donor for all microsomal cytochrome P450 (CYP or P450)‐catalyzed monooxygenase reactions. Disruption of the mouse __Cpr__ gene has been reported to cause prenatal developmental defects and embryonic lethali