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Measurement of cytochrome P450 and NADPH–cytochrome P450 reductase

✍ Scribed by Guengerich, F Peter; Martin, Martha V; Sohl, Christal D; Cheng, Qian

Book ID: 109946665
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 256 KB
Volume: 4
Category: Article
ISSN: 1750-2799
DOI: 10.1038/nprot.2009.121

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## Abstract Summary: NADPH‐cytochrome P450 reductase (CPR or POR) is the obligatory electron donor for all microsomal cytochrome P450 (CYP or P450)‐catalyzed monooxygenase reactions. Disruption of the mouse __Cpr__ gene has been reported to cause prenatal developmental defects and embryonic lethali