Nad(p)+-nad(p)h models. 50. Stereo-controlled reduction of methyl 2-oxo-3-methylpentanoate
✍ Scribed by Atsuyoshi Ohno; Hee Lee Joung; Tsuneo Yasuma; Shinzaburo Oka
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 214 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Racemic and optically active title compound was reduced with chiral and achiral NAD(P)H models.
The composition of diastereomers in the product was determined and the steric relationship is discussed.
📜 SIMILAR VOLUMES
## Abstract Experimental verification of chirality in 2,4‐dimethyl‐3‐carbamoylpyridinium cations.
## Abstract Pyrrolidinium salts derived from a series of 17‐substituted Δ^4^‐3‐ketosteroids are reduced by 1‐benzyl‐1,4‐dihydronicotinamide (BNAH) and 2,6‐dimethyl‐3,5‐diethoxycarbonyl‐1,4‐dihydropyridine (Hantzsch ester, 1 eq.) to the corresponding isomeric 5α‐ and 5β‐enamines which hydrolyse to t