𝔖 Bobbio Scriptorium
✦   LIBER   ✦

N-(n-benzylpiperidin-4-yl)-2-[18f]fluorobenzamide: a potential ligand for pet imaging of breast cancer

✍ Scribed by Chyng-Yann Shiue; Grace G Shiue; Francois Benard; Sophie Visonneau; Daniela Santoli; Abass A Alavi


Book ID
117687654
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
236 KB
Volume
27
Category
Article
ISSN
0969-8051

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


N-Arylation of indoles with 4-[18F]fluor
✍ Frank R. Wüst; Torsten Kniess 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 149 KB

## Abstract The palladium‐mediated __N__‐arylation of indoles with 4‐[^18^F]fluoroiodobenzene as a novel radiolabelling method has been developed. Optimized reaction conditions were elaborated by variation of different catalyst systems (CuI/1,2‐diamines and Pd~2~(dba)~3~/phosphine ligands), bases a

Synthesis and preliminary in vivo evalua
✍ M. Vandecapelle; F. Dumont; F. De Vos; K. Strijckmans; D. Leysen; K. Audenaert; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 138 KB 👁 1 views

## Abstract 4‐Fluoro‐__N__‐{2‐[4‐(6‐trifluoromethylpyridin‐2‐yl)piperazin‐1‐yl]ethyl}benzamide is a full 5‐HT~1A~ agonist with high affinity (__pK__~__i__~=9.3), selectivity and a __c__ log __P__ of 3.045. The corresponding PET radioligand 4‐[^18^F]fluoro‐__N__‐{2‐[4‐(6‐trifluoromethylpyridin‐2‐yl)