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N-myc gene amplification and other prognosis-associated factors in neuroblastoma

✍ Scribed by Eiso Hiyama; Takashi Yokoyama; Tory Ichikawa; Tetsuya Ishii; Keiko Hiyama


Book ID
115991516
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
548 KB
Volume
25
Category
Article
ISSN
0022-3468

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In neuroblastoma, N-myc amplification has been found to be strikingly associated with rapid tumour progression and poor prognosis. Recent studies have demonstrated that cell proliferative activity also significantly predicts the clinical outcome in patients with neuroblastoma. In order to define the