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Human neuroblastoma cell lines that express N-myc without gene amplification

✍ Scribed by Randal K. Wada; Robert C. Seeger; Garrett M. Brodeur; Peggy A. Einhorn; Sylvia A. Rayner; Mary M. Tomayko; C. Patrick Reynolds


Book ID
102670173
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
1011 KB
Volume
72
Category
Article
ISSN
0008-543X

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N-myc amplification and cell proliferati
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In neuroblastoma, N-myc amplification has been found to be strikingly associated with rapid tumour progression and poor prognosis. Recent studies have demonstrated that cell proliferative activity also significantly predicts the clinical outcome in patients with neuroblastoma. In order to define the