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N-Methyl-d-aspartate receptor subunit- and neuronal-type dependence of excitotoxic signaling through post-synaptic density 95

✍ Scribed by Jing Fan; Oana Cristina Vasuta; Lily Y. J. Zhang; Liang Wang; Ashley George; Lynn A. Raymond


Book ID
111184231
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
557 KB
Volume
115
Category
Article
ISSN
0022-3042

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N-Methyl-D-aspartate (NMDA) at a subtoxic concentration (100 mM) promotes neuronal survival against glutamate-mediated excitotoxicity via a brain-derived neurotrophic factor (BDNF) autocrine loop in cultured cerebellar granule cells. The signal transduction mechanism(s) underlying NMDA neuroprotecti