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N-methyl-d-aspartate receptor NR2B subunit gene GRIN2B in schizophrenia and bipolar disorder: Polymorphisms and mRNA levels

✍ Scribed by Livia Martucci; Albert H.C. Wong; Vincenzo De Luca; Olga Likhodi; Gregory W.H. Wong; Nicole King; James L. Kennedy


Book ID
119362675
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
145 KB
Volume
84
Category
Article
ISSN
0920-9964

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## Abstract The __N__‐methyl‐d‐aspartate glutamate receptors (NMDAR) act in the CNS as regulators of the release of neurotransmitters such as dopamine, noradrenaline, acetylcholine, and GABA. It has been suggested that a weakened glutamatergic tone increases the risk of sensory overload and of exag