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An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray

✍ Scribed by Qin, Shengying; Zhao, Xu; Pan, Yuxi; Liu, Jianhua; Feng, Guoyin; Fu, Jingchun; Bao, Jiying; Zhang, Zhizhou; He, Lin


Book ID
110026322
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
158 KB
Volume
13
Category
Article
ISSN
1018-4813

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N-methyl-d-aspartate receptor NR1 subuni
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## Abstract The __N__‐methyl‐d‐aspartate glutamate receptors (NMDAR) act in the CNS as regulators of the release of neurotransmitters such as dopamine, noradrenaline, acetylcholine, and GABA. It has been suggested that a weakened glutamatergic tone increases the risk of sensory overload and of exag