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N-Methyl-d-aspartate Receptor Antagonists Have Variable Affect in 3-Nitropropionic Acid Toxicity

โœ Scribed by Payman Nasr; Timothy Carbery; James W. Geddes


Book ID
106484134
Publisher
Springer
Year
2008
Tongue
English
Weight
459 KB
Volume
34
Category
Article
ISSN
0364-3190

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The over-activation of glutamate receptors can lead to excitotoxic cell death and is believed to be involved in the progression of neurodegenerative events in the vulnerable hippocampus. Here, we used an in vitro slice model to study toxicity produced in the hippocampus by the mitochondrial toxin 3-