๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

N-hydroxymethyl derivatives of nitrogen heterocycles as possible prodrugs II: Possible prodrugs of allopurinol, glutethimide, and phenobarbital

โœ Scribed by Padam C. Bansal; Ian H. Pitman; Takeru Higuchi


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
318 KB
Volume
70
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Aqueous degradation of N-(hydroxymethyl)
โœ M.Niyaz Khan ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 488 KB

The conversion of N-(hydroxymethyl)phthalimide (NHPH) to phthalimide could not be detected within 300 s at pH 9.0, whereas in 0.18 M NaOH complete conversion of NHPH to phthalimide was observed within 50 s. In the presence of 0.2-0.4 M 1,4-diazabicyclo[2.2.2]octane buffer solutions (pH 9.30-9.54), 4