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N-Heterocyclic analogues as peptide deformylase inhibitors: Molecular modeling, synthesis and antibacterial evaluation

โœ Scribed by Singh, Anuradha; Yadav, Madhu; Singh, Preeti; Srivastava, Ritika; Singh, Nidhi; Verma, Rajesh; Singh, Ramendra K


Book ID
125398315
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
87 KB
Volume
14
Category
Article
ISSN
1471-2334

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โœ Linliang Yu; Weicheng Zhou; Zhenyu Wang ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 285 KB

The drug resistant bacteria pose a severe threat to human health. The increasing resistance of those pathogens to traditional antibacterial therapy renders the identification of new antibacterial agents with novel antibacterial mechanisms an urgent need. In this study, a series of (2S)-N-substituted