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N-Acylation of 4-alkylidene-β-lactams: unexpected results

✍ Scribed by Gianfranco Cainelli; Daria Giacomini; Massimo Gazzano; Paola Galletti; Arianna Quintavalla

Book ID
104254147
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
165 KB
Volume
44
Category
Article
ISSN
0040-4039

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✦ Synopsis

This paper describes the different reactivity of E-and Z-4-alkylidene-b-lactams in acylation reactions under basic conditions. The E isomer is readily acylated, whereas the Z reacted sluggishly rearranging to the corresponding oxazin-6-one. The N-acylation of Z isomers was successfully obtained with oxalyl-or malonyl chlorides in benzene at reflux.

📜 SIMILAR VOLUMES

N-Acylation of 4-Alkylidene-β-lactams: U
N-Acylation of 4-Alkylidene-β-lactams: Unexpected Results.
✍ Gianfranco Cainelli; Daria Giacomini; Massimo Gazzano; Paola Galletti; Arianna Q 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 110 KB

## Abstract For Abstract see ChemInform Abstract in Full Text.