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N-acetylglucosamine and the substrate-site hypothesis for the control of insulin biosynthesis and secretion

โœ Scribed by I.H. Williams; S.J.H. Ashcroft

Book ID
115908326
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
468 KB
Volume
87
Category
Article
ISSN
0014-5793

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A method for the synthesis and purification of large quantities of four radiolabeled substrates for quantitation of uncovering enzyme is described. Four substrates, [3H]GlcNAc-alpha-P-Man alpha Me, [3H]GlcNAc-alpha-P-uteroferrin, [3H]GlcNAc alpha-P-Man alpha 1-2Man-O-Me, and [3H]GlcNAc alpha-P-Man9G