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N-Acetylcysteine Inhibits in Vivo Nitric Oxide Production by Inducible Nitric Oxide Synthase

โœ Scribed by Stefania Bergamini; Cristina Rota; Raffaella Canali; Mariagrazia Staffieri; Francesca Daneri; Anna Bini; Fabiola Giovannini; Aldo Tomasi; Anna Iannone


Book ID
115642131
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
220 KB
Volume
5
Category
Article
ISSN
1089-8603

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It has been previously demonstrated that microglia and astrocytes produce micromolar amounts of nitric oxide in vitro. In this study, we demonstrate that primary rat oligodendrocytes can be stimulated to produce iNOS mRNA as detected by Northern blot and in situ hybridization analysis and a 131-kDa