N -acetylcysteine attenuates subcutaneous administration of bleomycin-induced skin fibrosis and oxidative stress in a mouse model of scleroderma
✍ Scribed by Zhou, C.-F.; Yu, J.-F.; Zhang, J.-X.; Jiang, T.; Xu, S.-H.; Yu, Q.-Y.; Zhu, Q.-X.
- Book ID
- 121726180
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 354 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0307-6938
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## Abstract ## Objective Recently, we found that human dermal fibroblasts (HDFs) express melanocortin 1 receptors (MC‐1R) that bind α‐melanocyte–stimulating hormone (α‐MSH). In search of novel therapies for scleroderma (systemic sclerosis [SSc]), we used the bleomycin (BLM) model to investigate th