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N-ACETYL TRANSFERASE AND GLUTATHIONE S-TRANSFERASE GENETIC VARIANTS AND OUTCOME OF BLADDER CANCER

โœ Scribed by C. Murta-Nascimento; F.X. Real; M. Kogevinas; M. Garcia-Closas; N. Rothman; J. Lloreta; A. Tardon; C. Serra; M. Dosemeci; D. Silverman; A. Carrato; N. Malats

Book ID
119617302
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
47 KB
Volume
5
Category
Article
ISSN
1569-9056

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Interindividual differences in bladder cancer susceptibility may be partly mediated through polymorphic variability in the metabolism of carcinogens. N-acetyl transferase-2 (NAT2) has been extensively studied as a risk factor in this context, but the results are inconsistent. In some studies the fai