Genetic polymorphisms of glutathioneS-transferase T1 and bladder cancer risk: a meta-analysis
β Scribed by Fang-fang Zeng; Sheng-yuan Liu; Wen Wei; Song-po Yao; Shui Zhu; Ke-shen Li; Gang Wan; Hai-tao Zhang; Min Zhong; Bin-you Wang
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 316 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0372-8722
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Interindividual differences in bladder cancer susceptibility may be partly mediated through polymorphic variability in the metabolism of carcinogens. N-acetyl transferase-2 (NAT2) has been extensively studied as a risk factor in this context, but the results are inconsistent. In some studies the fai
Glutathione S-transferases (GSTs) belong to a superfamily of detoxification enzymes that provide critical defences against a large variety of chemical carcinogens and environmental toxicants. GSTs are present in most epithelial tissues of the human gastrointestinal tract. We investigated association