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N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as Potent Selective, Inhibitors of JNK2 and JNK3.

✍ Scribed by John A. Christopher; et al. et al.


Publisher
John Wiley and Sons
Year
2007
Weight
18 KB
Volume
38
Category
Article
ISSN
0931-7597

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✍ Ibolya Prauda; JΓ³zsef Reiter πŸ“‚ Article πŸ“… 2003 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 105 KB

## Abstract 5′‐Mercapto‐1β€²__H__‐1,2,4‐triazol‐3′‐yl‐isoquinolinium salts **(6)** were synthesised by the reaction of __ortho__‐acyl phenylacetones **(2)** or the corresponding pyrylium salts **(3)** and 5‐amino‐2,3‐dihydro‐1__H__‐1,2,4‐triazole‐3‐thione **(5)**. Treatment of thioles **6** withΞ±,ω‐d