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N-(2-Hydroxyethyl)phenazinium derivatives of oligonucleotides as effectors of the sequence-specific modification of nucleic acids with reactive oligonucleotide derivatives

โœ Scribed by I.V. Kutyavin; M.A. Podyminogin; Yu.N. Bazhina; O.S. Fedorova; D.G. Knorre; A.S. Levina; S.V. Mamayev; V.F. Zarytova


Book ID
115920371
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
291 KB
Volume
238
Category
Article
ISSN
0014-5793

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โœ V. V. Vlassov; N. D. Kobetz; E. L. Chernolovskaya; S. G. Demidova; R. G. Borisso ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 301 KB

Chemical modification of the chromatin DNA with alkylating derivatives of oligothymidylate (pT)16 and oligoadenylate (pA)16 bearing 4-(N-2-chloroethyl-N-methylamino)benzylphosphamide group at the 5'-phosphate has been investigated. It was found that the derivatives do react with DNA in chromatin. Th