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N-[2-(4-Methoxyphenoxy)ethyl]acetamide

✍ Scribed by Shang, Zhen-Hua ;Lv, Hai-Jun ;Gao, Jin-Long

Publisher: International Union of Crystallography
Year: 2007
Tongue: English
Weight: 428 KB
Volume: 63
Category: Article
ISSN: 1600-5368
DOI: 10.1107/s1600536807022726

No coin nor oath required. For personal study only.

✦ Synopsis

The title compound, C 11 H 15 NO 3 , was synthesized from 4methoxyphenol and 2-methyl-4,5-dihydrooxazole under nitrogen. There are two independent molecules in the asymmetric unit, which are connected into one-dimensional chains via intermolecular N-HÁ Á ÁO hydrogen bonds.

Related literature

Our interest in nefazodone, which is a type of antidepressant (Madding, 1986), prompted us to synthesize and determine the crystal structure of the title compound.

Experimental

Crystal data C 11 H 15 NO 3 M r = 209.24 Monoclinic, P2 1 =c a = 6.0861 (13) A b = 49.810 (10) A c = 7.4043 (15) A = 90.386 (4) V = 2244.6 (8) A ˚3 Z = 8 Mo K radiation = 0.09 mm À1 T = 294 (2) K 0.26 Â 0.24 Â 0.20 mm Data collection Bruker SMART CCD diffractometer Absorption correction: multi-scan (SADABS; Bruker, 1997) T min = 0.977, T max = 0.982 12862 measured reflections 4592 independent reflections 2442 reflections with I > 2(I) R int = 0.043 Refinement R[F 2 > 2(F 2 )] = 0.056 wR(F 2 ) = 0.090 S = 1.03 4592 reflections

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