Voltage dependent potassium currents were recorded using the wholecell mode of the patch-clamp technique for the first time from endfeet of Muller cells dissociated from the frog retina. Recordings from intact cells and isolated endfeet indicate that the inward rectifier potassium channel is the dom
Müller Cell Function during Spreading Depression in Frog Retina
✍ Scribed by Shigeo Mori, William H. Miller and Tsuneo Tomita
- Book ID
- 123653949
- Publisher
- National Academy of Sciences
- Year
- 1976
- Tongue
- English
- Weight
- 950 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/65898
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Whereas in the brain, the activity of the neurons is supported by several types of glial cells such as astrocytes, oligodendrocytes, and ependymal cells, the retina (evolving from the brain during ontogenesis) contains only one type of macroglial cell, the Müller (radial glial) cells, in most verteb
Mu ¨ller (radial glial) cells span the retina from the outer to the inner limiting membranes. They are the only glial cells found in the amphibian retina. The thickness of the frog (Rana pipiens) retina decreases by a factor of about four from the center to the periphery. Thus, Mu ¨ller cells were i
## Abstract The present study was aimed at characterizing the GABA~A~ receptor‐mediated currents in acutely isolated glial (Müller) cells of the human retina and investigating their subcellular localization across the Müller cell membrane. Extracellular application of GABA evoked two current respon